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Thymosin Alpha-1
35,00 €
Thymosin Alpha-1 is a naturally occurring 28-amino acid peptide originally isolated from thymic tissue. Researched for immune modulation, T-cell maturation, and antiviral properties. 5mg lyophilized powder, ≥99% purity.
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Thymosin Alpha-1—
35,00 €
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≥99% Purity
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Characteristics
| Molecular Formula | C129H215N33O55 |
| CAS | 62304-98-7 |
| Molar Mass | 3108.28 g/mol |
| Amino Acid Sequence | Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn |
| Synonyms | Tα1, Thymalfasin, Zadaxin |
| Solubility | Soluble in water |
| Organoleptic Profile | White powder |
| Physical Form | Lyophilized powder |
How does Thymosin Alpha-1 work?
Thymosin Alpha-1 is a 28-amino acid peptide first isolated from Thymosin Fraction 5 by Allan Goldstein in 1977. It plays a central role in T-cell development and immune regulation.
The peptide activates dendritic cells and enhances T-cell differentiation, particularly of CD4+ and CD8+ subsets. It stimulates natural killer (NK) cell activity and modulates cytokine production, shifting immune responses toward a Th1 phenotype.
Thymosin Alpha-1 acts on Toll-like receptors (TLR2, TLR9) to enhance both innate and adaptive immunity. Its immunomodulatory properties are distinct from immunosuppressants — it restores immune balance rather than broadly suppressing immune function.
References
- 1Goldstein AL, et al. "Thymosin α1: isolation and sequence analysis of an immunologically active thymic polypeptide" Proceedings of the National Academy of Sciences. 1977. doi:10.1073/pnas.74.2.725
- 2Garaci E, et al. "Thymosin alpha 1 in the treatment of cancer: from basic research to clinical application" International Journal of Immunopharmacology. 2000. doi:10.1016/S0192-0561(00)00058-3
- 3Tuthill C, et al. "Thymalfasin: biological properties and clinical applications" International Immunopharmacology. 2020. doi:10.1016/j.intimp.2020.107104
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All products on this site are for research and development use only. Products are not for human consumption of any kind. The statements made on this website have not been evaluated by the US Food and Drug Administration or the European Medicines Agency. Products are not intended to diagnose, treat, cure, or prevent any disease.
